Background: Brain cancers represent a formidable oncological challenge characterized by their aggressive nature and resistance to conventional therapeutic interventions.The tumor microenvironment has emerged as a critical determinant of tumor progression and treatment efficacy.Within this complex ecosystem, microglia and macrophages play fundamenta
Abstract Background Patterns of mtDNA variation within a species reflect long-term population structure, but may also be influenced by maternally inherited endosymbionts, such as Wolbachia.These bacteria often alter host reproductive biology and can drive particular mtDNA haplotypes through populations.We investigated the impacts of Wolbachia infec
Over the past two decades, southeastern Nigeria has witnessed huge economic losses due to severe flooding caused by climate change.Understanding the contribution of climate change to flooding is critical for runoff utilization and control, especially in the tropics.This study is focused on quantifying the amount of flooding contributed by climate c
Vicagrel, a novel acetate derivative of clopidogrel, exhibits a favorable safety profile and excellent antiplatelet activity.Studies aim at identifying genetic and non-genetic factors affecting vicagrel metabolic here enzymes Cytochrome P450 2C19 (CYP2C19), Carboxylesterase (CES) 1 and 2 (CES1 and CES2), which may potentially lead to altered pharma
In carrying out internal supervision duties, SPI UIN Sunan Kalijaga Yogyakarta innovates by carrying out digital document-based supervision using the Google here Drive service.SPI auditors often felt problems in using Google Drive, namely having to check the completeness of financial accountability documents manually one by one by opening a file on